Over 5 Years
Since Published

Unique Features of the Folding Landscape of a Repeat Protein Revealed by Pressure Perturbation

The volumetric properties of proteins yield information about the changes in packing and hydration between various states along the folding reacti... (more)

Catherine Royer Doug Barrick Catherine Royer and 1 other
Over 5 Years
Since Published

Structural Plasticity of Staphylococcal Nuclease Probed by Perturbation by Pressure and Ph

The ionization of internal groups in proteins can trigger conformational change. Despite this being the structural basis of most biological energy... (more)

Catherine Royer Catherine Royer
Over 4 Years
Since Published

Nonadditive Entropies Yield Probability Distributions with Biases Not Warranted by the Data

Different quantities that go by the name of entropy are used in variational principles to infer probability distributions from limited data. Shore... (more)

Kingshuk Ghosh Kingshuk Ghosh
Over 6 Years
Since Published

Kinetic Consequences of Native State Optimization of Surface-exposed Electrostatic Interactions in the Fyn Sh3 Domain

Optimization of surface exposed charge.charge interactions in the native state has emerged as an effective means to enhance protein stability; but... (more)

Hue-sun Chan George Makhatadze Hue-sun Chan and 1 other
Over 3 Years
Since Published

Non-native Structure Appears in Microseconds during the Folding of E. Coli Rnase H

The folding pathway of Escherichia coli RNase H is one of the best experimentally characterized for any protein. In spite of this, spectroscopic s... (more)

Susan Marqusee Bob Matthews Osman Bilsel Susan Marqusee and 2 others
Over 5 Years
Since Published

High Pressure Saxs Studies of Folded and Unfolded Ensembles of Proteins

A structural interpretation of the thermodynamic stability of proteins requires an understanding of the structural properties of the unfolded stat... (more)

Catherine Royer Catherine Royer
Almost 5 Years
Since Published

Perspective: Reaches of Chemical Physics in Biology

Chemical physics as a discipline contributes many experimental tools, algorithms, and fundamental theoretical models that can be applied to biolog... (more)

Dave Thirumalai Martin Gruebele Dave Thirumalai and 1 other
Almost 6 Years
Since Published

Native State Conformational Heterogeneity of Hp35 Revealed by Time-resolved Fret.

The villin headpiece subdomain (HP35) has become one of the most widely used model systems in protein folding studies, due to its small size and u... (more)

Feng Gai Feng Gai
5 Years
Since Published

Stepwise Protein Folding at near Amino Acid Resolution by Hydrogen Exchange and Mass Spectrometry

The kinetic folding of ribonuclease H was studied by hydrogen exchange (HX) pulse labeling with analysis by an advanced fragment separation mass s... (more)

Walter Englander Susan Marqusee Walter Englander and 1 other
Almost 6 Years
Since Published

Molecular Mechanism for the Preferential Exclusion of Osmolytes from Protein Surfaces

Trimethylamine N-oxide (TMAO) is a naturally occurring protecting osmolyte that stabilizes the folded state of proteins and also counteracts the d... (more)

Angel Garcia George Makhatadze Angel Garcia and 1 other

Showing 10 of 29 Publications