Over 4 Years
Since Published

Perspective: Reaches of Chemical Physics in Biology

Chemical physics as a discipline contributes many experimental tools, algorithms, and fundamental theoretical models that can be applied to biolog... (more)

Dave Thirumalai Martin Gruebele Dave Thirumalai and 1 other
Almost 5 Years
Since Published

Stepwise Protein Folding at near Amino Acid Resolution by Hydrogen Exchange and Mass Spectrometry

The kinetic folding of ribonuclease H was studied by hydrogen exchange (HX) pulse labeling with analysis by an advanced fragment separation mass s... (more)

Walter Englander Susan Marqusee Walter Englander and 1 other
Over 4 Years
Since Published

Nonadditive Entropies Yield Probability Distributions with Biases Not Warranted by the Data

Different quantities that go by the name of entropy are used in variational principles to infer probability distributions from limited data. Shore... (more)

Kingshuk Ghosh Kingshuk Ghosh
Almost 5 Years
Since Published

Principles of Maximum Entropy and Maximum Caliber in Statistical Physics

The variational principles called maximum entropy (MaxEnt) and maximum caliber (MaxCal) are reviewed. MaxEnt originated in the statistical physics... (more)

Kingshuk Ghosh Kingshuk Ghosh
Almost 6 Years
Since Published

Small-angle X-ray Scattering and Single-molecule Fret Spectroscopy Produce Highly Divergent Views of the Low-denaturant Unfolded State

The results of more than a dozen single-molecule Forster resonance energy transfer (smFRET) experiments suggest that chemically unfolded polypepti... (more)

Tobin Sosnick Tobin Sosnick
Over 5 Years
Since Published

Native State Conformational Heterogeneity of Hp35 Revealed by Time-resolved Fret.

The villin headpiece subdomain (HP35) has become one of the most widely used model systems in protein folding studies, due to its small size and u... (more)

Feng Gai Feng Gai
Over 6 Years
Since Published

Physical Limits of Cells and Proteomes

What are the physical limits to cell behavior? Often, the physical limitations can be dominated by the proteome, the cell's complement of proteins... (more)

Kingshuk Ghosh Kingshuk Ghosh
6 Years
Since Published

Kinetic Consequences of Native State Optimization of Surface-exposed Electrostatic Interactions in the Fyn Sh3 Domain

Optimization of surface exposed charge.charge interactions in the native state has emerged as an effective means to enhance protein stability; but... (more)

Hue-sun Chan George Makhatadze Hue-sun Chan and 1 other
7 Years
Since Published

Size and Sequence and the Volume Change of Protein Folding

The application of hydrostatic pressure generally leads to protein unfolding, implying, in accordance with Le Chatelier's principle, that the unfo... (more)

Catherine Royer Doug Barrick Angel Garcia Catherine Royer and 2 others
Over 5 Years
Since Published

Effect of Internal Cavities on Folding Rates and Routes Revealed by Real-time Pressure-jump Nmr Spectroscopy

The time required to fold proteins usually increases significantly under conditions of high pressure. Taking advantage of this general property of... (more)

Catherine Royer Angel Garcia Catherine Royer and 1 other

Showing 20 of 29 Publications